Antioxidant and Anticancer Potential of Methanolic Leaf Extract of Moringa concanensis Nimmo Against Human Breast Cancer Cell Line MCF-7
S Vijayakumar1, V Bhuvaneshwari1*, A Sumathi2
1Department of Biotechnology, Kongunadu Arts and Science College, Coimbatore-641 029, Tamil Nadu, India
2Department of Biotechnology, Hindustan College of Arts and Science, Coimbatore-641 028. TamilNadu, India
Received: 20th April, 17; Revised 24th May, 17, Accepted: 12th June, 17; Available Online:25th June, 2017
Breast cancer is one of the major health problems among women in both developed and developing countries. The objective of the present investigation is focused on the DPPH Radical Scavenging Activity and anticancer effect of the methanolic extract of Moringa concanensis Nimmo leaves against Breast cancer (MCF-7) cell line.
The study was facilitated by collecting the plant sample and subjected to crude extraction. The anticancer activity of the crude methanolic leaf extract of M. concanensis against MCF- 7 cell line was examined by MTT assay. The present study confirms that the crude leaf extract of M. concanensis has potential anticancer activity against MCF- 7 cell lines while compared to the control. M. concanensis leaves possess remarkable anticancer property which may lead to development of novel compounds as natural phytomedicine.
Keywords: Moringa concanensis, Breast cancer, DPPH, MCF- 7