Volume9,Issue6,Article25

Phytochemical Studies on Nerium oleander L. Using GC-MS 

Goraksh J Hase*, Keshav K Deshmukh, Raghunath D Pokharkar, Tukaram R Gaje, Narendra D Phatanagre

Department of Chemistry, S. N. Art’s, D.J. Malpani Commerce and B. N. Sarada Science College, Sangamner, Ahmednagar, Maharashtra, India. 

Received: 6th April, 17; Revised 9th June, 17, Accepted: 15th June, 17; Available Online:25th June, 2017 

ABSTRACT

Phytoconstituents are chemical compounds often referred to as secondary metabolites. Fifty eight bioactive phytochemical compounds were identified in the solvent free extract of Nerium Oleander L. root using Keshav Narean Apparatus3 [IP no. 2343/MUM/2013A] .The identification of phytochemical compounds is based on the peak area, retention time, molecular weight and molecular formula. A wide range of fatty acids, heterocyclic compound which are having anticancer, anti-fungal, anti-inflammatory and antibiotic activity were identified so that it can be recommended as a plant of phytopharmaceutical importance. The GCMS analyse Fifty eight phytochemical compounds in Nerium oleander L. root extract. The major phytoconstituents were 2-methoxy-5-methyl phenol and isomers (2.92%), 2, 6-dimethoxyphenyl ester (4.47%), trans-Isogenol (4.89%),5-ter-butylpyrogallol(2.25%),2-hydroxy-4-isopropyl-7 methoxytropone (3.72%),l-(+)-ascorbic-acid-2,6-dihexadecanoate,(4.47%),trans-Isogenol(4.89%),2,3,5-trimetho oxyamphetamine (2.25%), 2-hydroxy-4-isopropyl-7-methoxytropone (3.72 %), Oleic acid(1.09 %), 2-( 9,12- octadecadienyloxy)-,(Z,Z)- ethanol (9.48 %), 9-hexadecenoic acid (2.24%), 9-octadecenamide (3.13%), α-amyrin (10.85 %). 

Keywords: Phytoconstituents, GC-MS, phytopharmaceutical, Nerium Oleander L.

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International Journal of Pharmacognosy and Phytochemical Research