International Journal of

Pharmacognosy and Phytochemical Research

e-ISSN: 0975 4873

p-ISSN: 2961-6069

Peer Review Journal

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Volume16,Issue2

1. Anxiety Explored: Understanding Classification, Effective Treatments, and the Healing Essence of Aromatherapy
Soni RK, Chauhan B
Abstract
This thorough literature review explores the complex field of anxiety, with particular attention to how it is classified, what kinds of treatments are available, and how aromatherapy and essential oils are becoming more and more important in managing anxiety. Anxiety disorders, which include everything from panic disorder and phobias to generalised anxiety disorder, constitute a substantial worldwide health burden. Complementary therapies are being investigated because traditional treatment options, which include psychotherapy, medicine, and lifestyle modifications, still have limits. Aromatherapy has gained attention for its potential to alleviate symptoms of anxiety. It is based on the therapeutic application of aromatic plant extracts. The classification of anxiety, traditional therapies, and the mechanisms underpinning aromatherapeutic interventions are all summarised in this review of recent studies. In order to give readers a thorough grasp of anxiety disorders, this review integrates psychology, pharmacology, and alternative medicine to examine the use of essential oils in anxiety management.

2. Phytochemical Screening and Anticonvulsant Studies of Sesbania Grandiflora Flower Extract on Albino Rats
Abhilash Sankerneni, Shakira Fathima Syeda, T. Sunitha, Ravindra S. Beedimani
Abstract
There is a high amount of plant biodiversity in India. Most traditional medical systems employ plant-based medicinal compounds as an integral part of their treatment regimens. Sesbania grandiflora is a plant in the Fabaceae family that has been used traditionally for a variety of therapeutic purposes. The goal of the current study was to examine phytochemical and phytochemical investigations on particular plants like Sesbania grandiflora. Water, ethanol, and chloroform were utilised as extractive solvents in the Soxhlet apparatus used for the investigation in order to extract plant components. The plant Sesbania grandiflora flowers extract was qualitatively determined using standard chemicals and procedures. The goal of the study was to ascertain whether the plant’s blossoms contained any chemical compounds and to look into the drug’s quality. The results showed that various floral extracts might contain flavonoids, sterols, tannins, alkaloids, and steroids, among other substances.
The objective of the study was to ascertain whether a chemical substance was present in the plant’s blooms and to look into the drug’s quality. The various floral extracts were discovered to contain flavonoids, sterols, tannins, alkaloids, and other compounds. The anticonvulsant properties of ethanolic, aqueous, and chloroform extracts of Sesbania grandiflora flowers (100 mg/kg) were tested using the pentylenetetrazol (PTZ) induced seizure model. The length of convulsion and seizure onset were significantly (*p < 0.01) reduced by the extracts. The study found that the blooms of Sesbania grandiflora have anticonvulsant properties.

3. Comparison between Dienogest and Progesterone Sustained Release in Management of Endometriosis
Debobroto Roy, Banhi Shikha Modak, Nupur Ghosh, Tapas Ghosh
Abstract
Introduction: Endometriosis is a chronic, recurrent disease associated with debilitating pain and severely reduced quality of life in many affected women. In the absence of a definitive cure, the main management options in endometriosis comprise surgery, hormone therapy, or a combination of these two approaches. Aims: Endometriosis is a debilitating disease with high recurrence rates requiring long-term management. Progestins such as dienogest are used empirically when first symptoms occur and post-surgery to reduce recurrence. This retrospective, practice-based study assessed the efficacy and safety of dienogest in women with endometriosis treated for at least 60 months. Materials and Method: The present study was a comparative study. This Study was conducted from 2years at Department of Gynae & OBST Burdawan Medical College, P.O. Rajabati Baburbag, Burdawan 713104. Result: In 36 months, the mean Estradiol (mean± s.d.) of patients was 36 ± 14 pg/mL. In 60 months, the mean Estradiol (mean± s.d.) of patients was 28 ± 15 pg/mL. In 36 months, the mean Luteinizing hormone (mean± s.d.) of patients was 4.1±3.9 mIU/mL. In 60 months, the mean Luteinizing hormone (mean± s.d.) of patients was 2.0±1.7 mIU/mL. In 36 months, the mean Follicle-stimulating hormone (mean± s.d.) of patients was 10±3.9 mIU/mL. In 60 months, the mean Follicle-stimulating hormone (mean± s.d.) of patients was 10±4.5 mIU/mL. Conclusion: In conclusion, both dienogest and progesterone sustained release are effective options in the management of endometriosis, each with distinct advantages. Dienogest, a synthetic progestin, is specifically designed for endometriosis treatment and has demonstrated efficacy in reducing pain and lesion size, with a favorable safety profile. Its daily oral administration offers convenience and consistent hormone levels. On the other hand, progesterone sustained release formulations provide a more natural approach by using bioidentical hormone therapy, potentially reducing the risk of side effects associated with synthetic progestins. This method also allows for less frequent dosing, which may enhance patient compliance.
The objective of the study was to ascertain whether a chemical substance was present in the plant’s blooms and to look into the drug’s quality. The various floral extracts were discovered to contain flavonoids, sterols, tannins, alkaloids, and other compounds. The anticonvulsant properties of ethanolic, aqueous, and chloroform extracts of Sesbania grandiflora flowers (100 mg/kg) were tested using the pentylenetetrazol (PTZ) induced seizure model. The length of convulsion and seizure onset were significantly (*p < 0.01) reduced by the extracts. The study found that the blooms of Sesbania grandiflora have anticonvulsant properties.

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